Search found 838 matches

by qetzal
Sat Mar 04, 2017 11:42 pm UTC
Forum: Serious Business
Topic: An essay against competition
Replies: 50
Views: 8810

Re: An essay against competition

qetzal: But that is exactly where we disagree. A computational process is a model that includes a computer plus information (both of them concrete material things). The model fits all three of your examples, although you have left out some of the components. The thought process uses information in ...
by qetzal
Tue Feb 21, 2017 10:51 pm UTC
Forum: Serious Business
Topic: An essay against competition
Replies: 50
Views: 8810

Re: An essay against competition

A human is not a thought process, any more than a computer is Microsoft Excel, or than a species' genome is evolution.
by qetzal
Sun Jan 29, 2017 8:35 pm UTC
Forum: Serious Business
Topic: An essay against competition
Replies: 50
Views: 8810

Re: An essay against competition

It's not that the explanations in your essay are too long. It's that they're not logical or persuasive. Regarding thought vs. evolution, you really only have a single paragraph (at the end of Chapter 10): The human thought process is more efficient than evolution. The difference in efficiency is the...
by qetzal
Sat Jan 28, 2017 6:12 pm UTC
Forum: Serious Business
Topic: An essay against competition
Replies: 50
Views: 8810

Re: An essay against competition

reval, A key difficulty, at least for me, is that you make many claims and assertions that are unsupported and not self-evident (if not simply wrong). Take this paragraph: "When I am advancing my genetic information, my motive is competitive. Always more are born than can live. When I am advanc...
by qetzal
Sat Jan 28, 2017 5:55 am UTC
Forum: Serious Business
Topic: An essay against competition
Replies: 50
Views: 8810

Re: An essay against competition

As noted previously, competition and cognition are not opposites and they're not mutually exclusive. Cognition is also not an alternative to evolution. Claiming that the thought process is "more efficient and powerful" than evolution is quit frankly nonsensical. It's a bit like claiming th...
by qetzal
Thu Apr 28, 2016 11:17 pm UTC
Forum: News & Articles
Topic: Supermyths: Myths About Debunking Myths
Replies: 30
Views: 5581

Re: Supermyths: Myths About Debunking Myths

Actually, I don't think you can blame the debunkers here at all. Consider that first, there was the myth that spinach has a lot of iron. Then, that myth was debunked, but it must have been debunked for good reasons. It couldn't have been debunked based on the misplaced decimal story, because that (a...
by qetzal
Thu Mar 03, 2016 10:07 pm UTC
Forum: Science
Topic: Problems in medical research:Tracking outcome switching
Replies: 90
Views: 8466

Re: Problems in medical research:Tracking outcome switching

To be blunt, what you're saying is wrong. ObvioUsly I'm explaining poorly, so please do some reading on your own. It's not easy to grasp, and I freely admit it took me quite a while to understand, but it's woth the effort.
by qetzal
Thu Mar 03, 2016 8:27 pm UTC
Forum: Science
Topic: Problems in medical research:Tracking outcome switching
Replies: 90
Views: 8466

Re: Problems in medical research:Tracking outcome switching

If we get p < 0.01 that means our difference highly likely (with 99.00 percent certainty) did not happen due to chance or random factors such as sampling error, but due to existing difference between population groups. This is wrong. As a starting point, try the Wikipedia article on p-value, which ...
by qetzal
Thu Mar 03, 2016 2:15 pm UTC
Forum: Science
Topic: Problems in medical research:Tracking outcome switching
Replies: 90
Views: 8466

Re: Problems in medical research:Tracking outcome switching

It sounds like you're conflating two distinct issues here. Publication bias, where negative results don't get published, can make us think an effect is real even when it's not. That's because we might only see the results of the few studies that randomly produce a false positive result, but we don'...
by qetzal
Wed Mar 02, 2016 4:31 am UTC
Forum: Science
Topic: Problems in medical research:Tracking outcome switching
Replies: 90
Views: 8466

Re: Problems in medical research:Tracking outcome switching

Your statement was "Reporting all studies is the only way we can judge whether the apparent statistical significance of one study is actually significant." My mistake as well, I used the term 'apparent statistical significance' - there is no apparent statistical significance - the differe...
by qetzal
Sun Feb 21, 2016 4:11 am UTC
Forum: Science
Topic: Problems in medical research:Tracking outcome switching
Replies: 90
Views: 8466

Re: Problems in medical research:Tracking outcome switching

Well first of all, hiding negative date is not the same as hiring corrupt or incompetent researchers to generate fraudulent data, which was HungryHobo's claim. Second, drug developers can and do manipulate which data they publish, but it's much harder for them to conceal negative data from the regul...
by qetzal
Sun Feb 21, 2016 1:16 am UTC
Forum: Science
Topic: Problems in medical research:Tracking outcome switching
Replies: 90
Views: 8466

Re: Problems in medical research:Tracking outcome switching

Yes, crap drugs to get through. I don't dispute that. I dispute that crap drugs frequently get through because drug companies can just hire a few corrupt, naïve, or incompetent researchers.
by qetzal
Sun Feb 21, 2016 12:01 am UTC
Forum: Science
Topic: Problems in medical research:Tracking outcome switching
Replies: 90
Views: 8466

Re: Problems in medical research:Tracking outcome switching

Once you've spent hundreds of millions getting to stage 3 trials there's a strong incentive to corrupt a few naive researchers and skew a few results if it means making back the cost's to that point. The marketing goons don't give a flying fuck if the drug works or not, all they care about is wheth...
by qetzal
Thu Dec 31, 2015 8:03 pm UTC
Forum: News & Articles
Topic: Creationists twist themselves into a knot
Replies: 11
Views: 4364

Re: Creationists twist themselves into a knot

I'm still trying to figure out who has made the argument that a cat can give birth to a chicken. I don't know about cats giving birth to chicken, but Utah State Sen. Chris Buttars thought he could refute evolution by saying, "We get different types of dogs and different types of cats, but you ...
by qetzal
Mon Dec 28, 2015 4:56 am UTC
Forum: Science
Topic: Data presentation (Graphical design guru needed!)
Replies: 8
Views: 2868

Re: Data presentation (Graphical design guru needed!)

Your X axis seems very problematic to me. The first interval spans 10k, the next 15, then 25, then 50, then 150, and then everything larger. Is there any justification for that? Seems to me your apparent increase in B and C may disappear if you used equivalent sized bins.
by qetzal
Fri Dec 25, 2015 4:30 am UTC
Forum: News & Articles
Topic: The profit ethic at work!
Replies: 55
Views: 9621

Re: The profit ethic at work!

That would be great if that holds up. From the little I've read though, it seems to still be in dispute. E.g. See https://www.bakerlaw.com/files/uploads/ ... elgene.pdf.

But IANAL.
by qetzal
Thu Dec 24, 2015 3:27 pm UTC
Forum: News & Articles
Topic: The profit ethic at work!
Replies: 55
Views: 9621

Re: The profit ethic at work!

There are a few different issues at play here. In the case of Daraprim & Turing, that's a drug that's off-patent. Ordinarily, a generics drug manufacturer would have been able to get their own version of the same drug approved by FDA. Since the original version is (presumably) already proven to ...
by qetzal
Sun Dec 06, 2015 2:51 am UTC
Forum: News & Articles
Topic: The profit ethic at work!
Replies: 55
Views: 9621

Re: The profit ethic at work!

@sardia I don't see where your link says drug companies lobbied in favor of FDA's restricted distribution rules. And in any case, this link http://healthaffairs.org/blog/2015/10/21/the-daraprim-price-hike-and-a-role-for-antitrust/ sats Daraprim isn't covered by such FDA restrictions anyway. Skreli's...
by qetzal
Tue Nov 24, 2015 3:44 am UTC
Forum: Logic Puzzles
Topic: Escape the Frictionless Circle
Replies: 136
Views: 26582

Re: Escape the Frictionless Circle

Or, what if you rub one side of the gold block, making that side get warmer. Could that do anything? Maybe the higher temp of that side would slightly increase the (infinitesimal) evaporation rate of gold atoms, creating a *tiny* net force on that side? 😀 Edit: More seriously, would the following wo...
by qetzal
Mon Nov 23, 2015 11:00 pm UTC
Forum: News & Articles
Topic: My Friend was Killed in a Terrorist Attack
Replies: 9
Views: 4176

Re: My Friend was Killed in a Terrorist Attack

Yes, if you want people to sign this, the least you should do is back up the factual claims in the petition.
by qetzal
Mon Aug 24, 2015 2:11 am UTC
Forum: Logic Puzzles
Topic: Three Cards Trick
Replies: 15
Views: 2263

Re: Three Cards Trick

i think kamenf gave the clue above. Besides the order of the cards on the table, there's also the order that the Assistant names them. That allows 36 different combos. And that should be plenty because there are really only 17 permutations needed: 13 for the rank (2-A) and 4 for the suit.
by qetzal
Sun Aug 23, 2015 1:00 pm UTC
Forum: Science
Topic: Doctor/Quack/Shill Vitamin D?
Replies: 14
Views: 2962

Re: Doctor/Quack/Shill Vitamin D?

If he's recommending chiropracty, I'd strongly consider finding a new doc. Conventional chiropracty is quackery. They believe that all illnesses are due to blockages of "innate intelligence" and that they can be cured by adjusting your spine to unblock the flow. Which is baloney. Now, the...
by qetzal
Sat Aug 22, 2015 9:24 pm UTC
Forum: Science
Topic: Doctor/Quack/Shill Vitamin D?
Replies: 14
Views: 2962

Re: Doctor/Quack/Shill Vitamin D?

If he's recommending chiropracty, I'd strongly consider finding a new doc. Conventional chiropracty is quackery. They believe that all illnesses are due to blockages of "innate intelligence" and that they can be cured by adjusting your spine to unblock the flow. Which is baloney. Now, ther...
by qetzal
Sun Aug 09, 2015 11:32 pm UTC
Forum: Serious Business
Topic: The Ethics of Genetic Engineering
Replies: 215
Views: 36817

Re: The Ethics of Genetic Engineering

If your point is that directors won't spend money to ID genetic causes of diseases, for fear that will lead to people demanding genetic fixes for those diseases, I think you're wrong. There may be someone somewhere who's taken that position, but I don't believe it's a real issue. As for screening, I...
by qetzal
Mon Aug 03, 2015 2:18 pm UTC
Forum: Serious Business
Topic: The Ethics of Genetic Engineering
Replies: 215
Views: 36817

Re: The Ethics of Genetic Engineering

Spleen, Actually, I am in the US. And, having worked for roughly a decade in human gene therapy and closely related fields, I like to think I have some insight here as well. :) I completely agree that US & EU research organizations don't want to get involved in embryonic or germ-line genetic mod...
by qetzal
Sun Aug 02, 2015 1:23 pm UTC
Forum: Serious Business
Topic: The Ethics of Genetic Engineering
Replies: 215
Views: 36817

Re: The Ethics of Genetic Engineering

The only thing that would be considered shocking is that some boards of directors etc, do not even allow research in the genetic cause of a number of illnesses because there then would be a potential risk we might make a study coming up with a GM cure later on. Which in turn would make it possible ...
by qetzal
Sun Aug 02, 2015 1:11 pm UTC
Forum: Serious Business
Topic: Dairy or dairy-free alternative?
Replies: 37
Views: 9234

Re: Dairy or dairy-free alternative?

Sableagle wrote:Producing milk's incredibly inefficient in terms of water and land use...


Seems like the obvious choice is water.
by qetzal
Wed Jun 24, 2015 1:49 pm UTC
Forum: Science
Topic: Noise Muffling: Locked vs Unlocked Window
Replies: 13
Views: 2029

Re: Noise Muffling: Locked vs Unlocked Window

If your window is like some of mine, latching may also close it tighter, eliminating some gaps where the sound was coming through.
by qetzal
Sun May 10, 2015 5:21 am UTC
Forum: Science
Topic: Contamination of insulin pump cartridges
Replies: 23
Views: 3550

Re: Contamination of insulin pump cartridges

Zinc has no effect on monomer stability. It's possible it has some effect on dimer stability, but I doubt it. Zinc is excluded from the dimer interface. Zinc is just the cation of choice because that is how insulin exists natively. I searched a bit but couldn't find a good explanation of why Zn is ...
by qetzal
Sat May 09, 2015 9:16 pm UTC
Forum: Science
Topic: Contamination of insulin pump cartridges
Replies: 23
Views: 3550

Re: Contamination of insulin pump cartridges

There's plenty on sodium already for charge neutralization. I'm pretty sure they wouldn't bother adding zinc just for that. Most likely the zinc helps stabilize the monomers or something. I'd also guess that someone in pharma and/or FDA (and their equivalents in other countries) have already conside...
by qetzal
Sat May 09, 2015 3:11 pm UTC
Forum: Science
Topic: Contamination of insulin pump cartridges
Replies: 23
Views: 3550

Re: Contamination of insulin pump cartridges

The US label for Novolog says the following: NovoLog is a sterile, aqueous, clear, and colorless solution, that contains insulin aspart 100 Units/mL, glycerin 16 mg/mL, phenol 1.50 mg/mL, metacresol 1.72 mg/mL, zinc 19.6 mcg/mL, disodium hydrogen phosphate dihydrate 1.25 mg/mL, sodium chloride 0.58 ...
by qetzal
Thu Apr 30, 2015 1:59 pm UTC
Forum: Serious Business
Topic: Genetic use restriction technology (Suicide Seeds)
Replies: 22
Views: 7694

Re: Genetic use restriction technology (Suicide Seeds)

@ahammel: I don't disagree with any of that. I'll just say again that all those concerns relate to the introduced genes or traits, not to the method of introductoon. If it were possible to introduce the same genes/traits by non-GMO methods, all those issues would still apply, right? @Autolykos: AFAI...
by qetzal
Thu Apr 09, 2015 10:28 pm UTC
Forum: Science
Topic: Motion mountain: crackpot?
Replies: 26
Views: 12877

Re: Motion mountain: crackpot?

I humbly submit that if there's this much disagreement over what specific passages even mean, it's a bad textbook. Even uf the author isn't a crackpot.
by qetzal
Wed Apr 01, 2015 12:13 am UTC
Forum: News & Articles
Topic: Anglo-Saxon apothecary’s unguent effective against MRSA
Replies: 8
Views: 3432

Re: Anglo-Saxon apothecary’s unguent effective against MRSA

Not sure this is so surprising. Here's a paper from 70 years ago showing that onion and garlic have antibacterial properties.
by qetzal
Fri Mar 06, 2015 3:00 pm UTC
Forum: Serious Business
Topic: Genetic use restriction technology (Suicide Seeds)
Replies: 22
Views: 7694

Re: Genetic use restriction technology (Suicide Seeds)

I don't think it was really a bullshit reason. At least, not for everyone. I don't doubt that Monsanto et al. recognized that mechanisms to prevent escape could also be used to retain control. But I also clearly recall a lot of academic GMO researchers back in the 80s were very concerned about escap...
by qetzal
Fri Mar 06, 2015 3:21 am UTC
Forum: Science
Topic: Human Gut Microbiome: Essential or Not?
Replies: 31
Views: 4996

Re: Human Gut Microbiome: Essential or Not?

What happens if you recolonize adult germ-free mice with normal gut flora? Do they gain significant protection from pathogens? Is their immune dysfunction ameliorated at all?
by qetzal
Thu Mar 05, 2015 4:15 pm UTC
Forum: Serious Business
Topic: Genetic use restriction technology (Suicide Seeds)
Replies: 22
Views: 7694

Re: Genetic use restriction technology (Suicide Seeds)

Wouldn't it also be important to make sure that GMO crops aren't cross-pollinating with the "natural" versions surrounding the fields? We want to be ecologically safe, after all. Is that really specific to GMO crops though? Why is it necessary to prevent cross-pollination for GMOs, but no...
by qetzal
Sun Mar 01, 2015 5:18 am UTC
Forum: Science
Topic: Human Gut Microbiome: Essential or Not?
Replies: 31
Views: 4996

Re: Human Gut Microbiome: Essential or Not?

Interesting that Knight says two people may share as little as 10% of their gut microbes. Does that suggest that the major beneficial functions are fulfilled by a small fraction that's common to everyone? Or that many different microbes can fulfill the same functions more or less equivalently?
by qetzal
Sun Feb 22, 2015 4:02 pm UTC
Forum: Serious Business
Topic: The Ethics of Genetic Engineering
Replies: 215
Views: 36817

Re: The Ethics of Genetic Engineering

That's the beauty of it. The next generation could do the same procedure again for the next few sets of changes. They'll probably manage much more then, and even more the next one after, quite possibly due to advances made to the procedure by performing it. But how will you know if you really have ...
by qetzal
Sun Feb 22, 2015 1:38 pm UTC
Forum: Serious Business
Topic: The Ethics of Genetic Engineering
Replies: 215
Views: 36817

Re: The Ethics of Genetic Engineering

jseah, The problem, IMO, is that transforming "as many in as you can" is still going to be highly limited. I agree we could likely do that with a small number of different SNPs. But how much of an intelligence increase would we expect with only a few such changes? Even under the best of co...

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