Hifaleetin' thoughts

Things that don't belong anywhere else. (Check first).

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CombustibleLemons
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby CombustibleLemons » Fri Jan 29, 2010 3:52 am UTC

if I'm an organ doner could my lets say kidney go to another organ doner and so on and so forth so my kidney never dies?
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Ivora » Fri Jan 29, 2010 4:01 am UTC

Hit3k wrote:
Ivora wrote:Lately I can't sleep with the lights off.

Something... something is watching me. I know its something because I can see its shadow whenever I move my eye to the side...

Ever so gently.... it crawls back into obscurity, as if its afraid of being caught.

It's that bitch Edward Cunten Cullen.


Why on earth did you mention Twilight?!!!

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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby The Cat » Fri Jan 29, 2010 4:21 am UTC

Obviously that was directed toward a penguin. Look! That would make no sense.

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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Fossa » Fri Jan 29, 2010 7:30 am UTC

Amishdemon wrote:if I'm an organ doner could my lets say kidney go to another organ doner and so on and so forth so my kidney never dies?


If memory serves, no, no it can't.

Whenever your cells divide the DNA replication isn't perfect. The biggest problem is that every time your DNA is copied you lose a little bit off the end. Imagine a train driving up a some tracks scanning them so it can make an exact replica. When it reaches the end of the line the scanner never gets to the very end because the locomotive is in the way. So you copy all but the last 20 feet of thirty miles of track; no big deal, right?

The problem is that this happens rather frequently when we're talking about cells dividing. If I'm not mistaken this is one of the chief causes of aging (post-development). Your body loses the DNA necessary to keep it functioning the way it does in your twenties and thirties.

Interestingly enough, there is a way around this. Some cancer cells manage to replicate the full strand of DNA right up to the very edges. So yeah, aside from the whole "dividing uncontrollably to create deadly tumors" bit, cancer is kind of cool.

In fact, the cells that made up a woman's cervical cancer have survived for close to 60 years since her death. HeLa cells (formerly of a Miss Henrietta Lacks) have an active form of the enzyme telomerase so there is no incremental loss during cell division. This makes her cell line immortal which is pretty fricking handy when you're doing biomedical research and need a solid control. Her cancer cells have done everything from contributing to the polio vaccine to going into space. The only problem is Henrietta was never told they were going to make her tumour fucking immortal, which kind of sucks for her, I guess. Still, she's technically been into space, kind of, so I guess that makes up for it?

The Cat

Re: Fleeting/Random/Thoughts (Random like the plague)

Postby The Cat » Fri Jan 29, 2010 9:00 am UTC

I was thinking about the X360 discussion from the other day.

I do believe the problem to be with the hardware. If you look at the money spent on research and development, there is no question as to the intend of the designers. Furthermore, at stages, the software was absolutely corrupted. I'm sure it is obvious to the developers who were with the project from the beginning. Since this seems to have been a failure for them, I don't see why they would have a problem with another company redesigning the circuit board. That's what I don't get, they don't want it, but they don't want anyone else to have it? I wish someone could explain that!

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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Secateurs » Fri Jan 29, 2010 9:17 am UTC

The Cat wrote:That's what I don't get, they don't want it, but they don't want anyone else to have it? I wish someone could explain that!
Out of context explanation: human nature. As soon as someone else picks up that unwanted piece of junk you had, it attains value and you regret throwing it away.
(For TV references, see Friends, The Simpsons, and probably Family Guy or Futurama have done a scene about this)

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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Buddha with a bra on » Fri Jan 29, 2010 11:55 am UTC

Organ donarship: way to put bits of me into you while I gain less satisfaction from it. :P

(Having never give away any organs - who'd want mine, anyway - I cannot say how satisfyig it is.)
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Zohar » Fri Jan 29, 2010 2:21 pm UTC

I think it would be pretty cool to hang a picture that's tilted sideways, so that you'll hang it at an angle for it to be straight. It would be cooler if the tilt was only about 3 degrees or so, then no matter if you tried to straighten the frame or straighten the image, it would still look a bit off.

Also, what the fuck?? I just noticed a "U" shape shaved in my forearm! What the hell?? How did this happen?? I burned a pot the other day and had to use some strong cleaning solution on it, maybe it dripped off on me?
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Flightless_bird » Fri Jan 29, 2010 3:44 pm UTC

Zohar wrote:I think it would be pretty cool to hang a picture that's tilted sideways, so that you'll hang it at an angle for it to be straight. It would be cooler if the tilt was only about 3 degrees or so, then no matter if you tried to straighten the frame or straighten the image, it would still look a bit off.

Also, what the fuck?? I just noticed a "U" shape shaved in my forearm! What the hell?? How did this happen?? I burned a pot the other day and had to use some strong cleaning solution on it, maybe it dripped off on me?


Maybe it's the start of a long sentence that's going to show gradually?
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby SecondTalon » Fri Jan 29, 2010 4:33 pm UTC

U R Likly 2 Be Eten Bai A Gru.


The Dark Forces at work here are terrible spellers.
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby pseudoidiot » Fri Jan 29, 2010 4:37 pm UTC

I knew 'text speak' must have come from the devil.
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Sungura » Fri Jan 29, 2010 5:18 pm UTC

I WANT DATA.
NOW.
GIMME.
I don't care if my theory is right or wrong, I just want to get the dang data!
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby SecondTalon » Fri Jan 29, 2010 5:22 pm UTC

2, Toledo, and Orange.

Is that the data you wanted?
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Sungura » Fri Jan 29, 2010 5:25 pm UTC

Way better than nothing!
Thanks!

Edit: WOOO
I have non-data data!
(ie. I need to tweek my protocol, but I have proof stuff is /working/ which is better than what I have dealt with for the last months!)
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Chfan » Fri Jan 29, 2010 7:37 pm UTC

Fossa wrote:
Amishdemon wrote:if I'm an organ doner could my lets say kidney go to another organ doner and so on and so forth so my kidney never dies?


If memory serves, no, no it can't.

Whenever your cells divide the DNA replication isn't perfect. The biggest problem is that every time your DNA is copied you lose a little bit off the end. Imagine a train driving up a some tracks scanning them so it can make an exact replica. When it reaches the end of the line the scanner never gets to the very end because the locomotive is in the way. So you copy all but the last 20 feet of thirty miles of track; no big deal, right?

The problem is that this happens rather frequently when we're talking about cells dividing. If I'm not mistaken this is one of the chief causes of aging (post-development). Your body loses the DNA necessary to keep it functioning the way it does in your twenties and thirties.

Interestingly enough, there is a way around this. Some cancer cells manage to replicate the full strand of DNA right up to the very edges. So yeah, aside from the whole "dividing uncontrollably to create deadly tumors" bit, cancer is kind of cool.

In fact, the cells that made up a woman's cervical cancer have survived for close to 60 years since her death. HeLa cells (formerly of a Miss Henrietta Lacks) have an active form of the enzyme telomerase so there is no incremental loss during cell division. This makes her cell line immortal which is pretty fricking handy when you're doing biomedical research and need a solid control. Her cancer cells have done everything from contributing to the polio vaccine to going into space. The only problem is Henrietta was never told they were going to make her tumour fucking immortal, which kind of sucks for her, I guess. Still, she's technically been into space, kind of, so I guess that makes up for it?


Is that why even if medical technology gets radically better and we start living longer, we won't really be able to live forever?
Just FYI, the guy isn't avatar isn't me. But he seems pretty cool.

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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby SecondTalon » Fri Jan 29, 2010 7:55 pm UTC

Pretty much, yeah. If you could harness cancer, you'd be immortal. Sorta kinda, from my armchair half-interest in the subject.

I'm sure some biology major will come along and tell me why this is not the case.
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Fossa » Fri Jan 29, 2010 8:14 pm UTC

If I remember correctly there's ongoing research into creating an active version of telomerase to prevent aging on the cellular level. It's sort of held up by the fact that it frequently causes cancer. Like crazy amounts of cancer. Like every single cell in the tissue culture they're working with becoming cancerous at once crazy.

If they ever perfect that, though, hello immortality (and overcrowding, resource depletion, strict regulation on population growth with harsh penalties for unauthorized procreation, etc).

In the meantime, there's actually a similar effect brought about by something our bodies already have. It's a nifty little dipeptide called Carnosine. It's been shown to extend the Hayflick limit in human tissue. The Hayflick limit is the point that the cell runs out of "filler material" at the end of the DNA strands and starts losing critical bits of DNA (and thus, aging).

While it doesn't prevent the process completely by replacing the end material the way telomerase does, it does delay aging and does so without contributing to cancer. So yeah. Hooray Carnosine.

Of course, if you're a vegetarian you don't get much Carnosine in your diet as it's only found in high concentrations in muscle and brain tissue. So yeah, meat eaters should, on average, live longer. Or they would, anyway, if they didn't die of heart disease. Maybe this is where that whole concept of moderation comes into play...

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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Izawwlgood » Fri Jan 29, 2010 8:38 pm UTC

It should also be pointed out that telomerase isn't the only thing that contributes to longevity; for the example of kidneys, you are born with a set number of nephrons (the functional filtering unit of the kidney), and over time, you lose them (injury, disease, randomness). Merely causing cells to not become cancerous isn't always enough; sometimes, general wear and tear on a tissue is the culprit.
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Fossa » Fri Jan 29, 2010 9:04 pm UTC

Well telomerase and carnosine aren't about preventing cancer so much as they are about allowing unlimited (or in the case of carnosine, extended) cellular division without the degradation of DNA. This makes it theoretically possible for basic tissue to be immortal and not age.

Anything you're born with a set number of (like nephrons, I guess) is going to be a separate problem.

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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Whelan » Fri Jan 29, 2010 9:11 pm UTC

Surely if/when we become able to grow organs in the lab from stem cells then replacing worn out tissues will be possible?
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Link » Fri Jan 29, 2010 10:50 pm UTC

Whelan wrote:Surely if/when we become able to grow organs in the lab from stem cells then replacing worn out tissues will be possible?

Believe you me, they are working on that.. Of course, with that method, one major problem remains: the need for invasive surgery to replace organs. That said, research to slow ageing or stop it altogether is also ongoing. I wouldn't be surprised if a major breakthrough was reached some time this century.

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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Whelan » Fri Jan 29, 2010 10:56 pm UTC

Just in time for me to be old and bitter! Yay!
"I like to be understood whenever I open my mouth; I have a horror of blinding people with science"- Richard Dawkins
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Baldur » Sat Jan 30, 2010 12:35 am UTC

Ah, creepy old man. You were quite obviously drunk, I get that. You were booked on the seat across from me on the train, I don't mind that. What I did mind is your leg sliding against mine every five minutes. It was creepy. Also, did the big headphones not give away the fact that I didn't want to be disturbed?

Hearing an old man invite me back to his "boudoir" is about the creepiest thing ever. Seriously.
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Secateurs » Sat Jan 30, 2010 1:47 am UTC

I just realised that I know someone with the initials 'dvdp'. I wondered why it seemed vaguely familiar when I said it in my head.
And then my mind skipped straight to calculus.
It's a sad life I lead...

On another note, I need to try and spend $220 worth of book vouchers today :shock:. The bookstore I'm going to doesn't really have any textbooks though, so I'm guessing there won't be much that appeals to my chem/physics/maths interests.
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby pseudoidiot » Sat Jan 30, 2010 2:22 am UTC

Secateurs wrote:I just realised that I know someone with the initials 'dvdp'. I wondered why it seemed vaguely familiar when I said it in my head.
And then my mind skipped straight to calculus.
It's a sad life I lead...
It's sad that the first thing that popped into my head was 'dvda'.
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby emceng » Sat Jan 30, 2010 4:20 am UTC

pseudoidiot wrote:
Secateurs wrote:I just realised that I know someone with the initials 'dvdp'. I wondered why it seemed vaguely familiar when I said it in my head.
And then my mind skipped straight to calculus.
It's a sad life I lead...
It's sad that the first thing that popped into my head was 'dvda'.


Me too. Also, I spent around $250 at Half Price Books last year. That means I got around $500 of books. Which would be alot cooler if they weren't 90% pulp sci-fi shit I shouldn't bother reading in the first place.
When I became a man I put away childish things, including the fear of childishness and the desire to be very grown up. - CS Lewis

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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby The Cat » Sat Jan 30, 2010 4:41 am UTC

Weather coming in tomorrow, hope I can make it out. I would probably hike through feet of snow at this point.

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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby NecklaceOfShadow » Sat Jan 30, 2010 5:25 am UTC

Tomorrow:

Destination Linux

It shall be fun.
Significantly less weird than I used to be. Still pretty weird.

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πόσις, νεκρὸς δὲ τῆσδε δεξιᾶς χερός
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby SecondTalon » Sat Jan 30, 2010 5:44 am UTC

pseudoidiot wrote:
Secateurs wrote:I just realised that I know someone with the initials 'dvdp'. I wondered why it seemed vaguely familiar when I said it in my head.
And then my mind skipped straight to calculus.
It's a sad life I lead...
It's sad that the first thing that popped into my head was 'dvda'.
But.... Now you're a man!
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby crush pill » Sat Jan 30, 2010 5:50 am UTC

SecondTalon wrote:
pseudoidiot wrote:
Secateurs wrote:I just realised that I know someone with the initials 'dvdp'. I wondered why it seemed vaguely familiar when I said it in my head.
And then my mind skipped straight to calculus.
It's a sad life I lead...
It's sad that the first thing that popped into my head was 'dvda'.
But.... Now you're a man!

That was interesting.

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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Giant Speck » Sat Jan 30, 2010 7:01 am UTC

Is it just me, or does anyone else seem to think that Ke$ha is the drunk, white trash, party girl version of Taylor Swift?

I don't listen to pop music or even Top 40; however, I keep seeing Ke$ha's "Tik Tok" everywhere, so I decided to watch the entire music video.
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Teapot » Sat Jan 30, 2010 7:14 am UTC

I have pizza for breakfast!
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Jumble » Sat Jan 30, 2010 7:43 am UTC

Jumble wrote:Cold pizza - the breakfast of champions!

FT: Is it just me or is '3rd and Bird' the greatest abomination to ever scrape a hole through the bottom of the barrel of children's TV? As a parent, the attempts at singing in harmony are like finger-nails scraping down the blackboard of my soul.


I refer the right honourable lady to my earlier post (from back on page 1110)
Spoiler:
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Keybounce » Sat Jan 30, 2010 7:58 am UTC

Boy, this is an interesting (and long :-) thread.
Last edited by Keybounce on Sat Jan 30, 2010 8:12 am UTC, edited 1 time in total.
<this space on hold>

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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby suffer-cait » Sat Jan 30, 2010 7:59 am UTC

link, pl0x
ImageImageImageImageImage

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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby Xeio » Sat Jan 30, 2010 8:34 am UTC

Bah, I'm pathetic.

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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby wizardy42 » Sat Jan 30, 2010 10:32 am UTC

.
Last edited by wizardy42 on Wed Mar 18, 2015 3:22 am UTC, edited 1 time in total.

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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby phlip » Sat Jan 30, 2010 11:34 am UTC

I'm watching The Core on TV right now, and I just can't stop laughing.

Code: Select all

enum ಠ_ಠ {°□°╰=1, °Д°╰, ಠ益ಠ╰};
void ┻━┻︵​╰(ಠ_ಠ ⚠) {exit((int)⚠);}
[he/him/his]

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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby micco » Sat Jan 30, 2010 11:38 am UTC

Oh dear, I'll have to go to a dentist soon. I hate dentists...
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Re: Fleeting/Random/Thoughts (Random like the plague)

Postby brakos82 » Sat Jan 30, 2010 11:44 am UTC

Went to sleep at 10 PM
Time right now is 3:40 AM
I actually need to get up at 6:45 AM

Suddenly my insomnia from earlier this month has reversed itself somehow.
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