Fight infections with virus

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Fight infections with virus

Postby 3.14chan » Wed Jun 17, 2009 2:05 am UTC

How to heal an infection caused by a bacteria resistant to all antibiotics? Infect them with virus. Doctors in Eastern Europe have used lab-grown viruses to safely cure millions of wounds using bacteria's natural enemy.

Here is a 50min video (long but interesting)
http://www.ib4f.com/board/science/sci/topic/64723#72388

EDIT:
And a patent for the use of virus in dental hygiene
http://www.patentstorm.us/patents/48912 ... ption.html
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Re: Fight infections with virus

Postby 3.14chan » Wed Jun 17, 2009 2:19 am UTC

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Re: Fight infections with virus

Postby The Reaper » Wed Jun 17, 2009 5:26 am UTC

3.14chan wrote:One article from TimesOnline
http://www.timesonline.co.uk/tol/life_a ... 253212.ece

Nifty :3

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Re: Fight infections with virus

Postby 3.14chan » Wed Jun 17, 2009 1:10 pm UTC

Pseudomonas is sick, soon it will pass away :( :roll: :mrgreen:
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Re: Fight infections with virus

Postby BlackSails » Wed Jun 17, 2009 1:13 pm UTC

The technology is pretty old. I think it will have uses, but its pretty hard to use. First, you need to identify the bacteria. This alone can take too much time in some cases. Then you need the specific strain tailored to the type or subtype of bacteria. Then you need to deal with the virus getting to the right place in the body, which it cant alawys do. And even if it works, then you need to deal with the immune system as it reacts to loads of toxins in the blood from the lysed bacteria.


On the plus side, bacterial immunity shouldnt be a problem.

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Re: Fight infections with virus

Postby 3.14chan » Wed Jun 17, 2009 2:30 pm UTC

They use it on wounds so put it in the right place is not a problem.
Lised bacteria toxin will be released if you kill them anyway...

The good thing is that it kills bacteria that no antibiotic can kill.
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Re: Fight infections with virus

Postby Indon » Thu Jun 18, 2009 12:33 am UTC

I just hope the virus never determines that mankind is the true disease.

The impression I get is that the type of virus used here isn't likely to mutate, though, so at least the chances of a backfire of the treatment seem minimal - and even if it does, at worst it might eliminate a 'good' type of bacteria in the human body which could just get recultured.
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Re: Fight infections with virus

Postby 3.14chan » Thu Jun 18, 2009 1:57 am UTC

They do mutate, but this is good!
Each virus species evolved to attack one bacteria species. It will not attack another species of bacteria so it will never attack a animal/vegetal cell. It's like to be afraid of geting infected with a soy virus.

Antibiotics do destroy good bacteria from our body, virus would be more specific.

Yes, this is old technology, people thought that antibiotics were the answer and abandoned the virus. Today there are some bacteria immune to every antibiotic, but there is no bacteria immune to every virus because virus will evolve to find a way to multiply.
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Re: Fight infections with virus

Postby Izawwlgood » Thu Jun 18, 2009 2:14 am UTC

There are plenty of bacteria immune to plenty of viruses. And, plenty of bacteria evolve to be immune to a virus they were once susceptible to.

This idea is pretty old and I think can sort of be equated to fighting your way out of a house made of thick glass with a megaphone cranking a single, random tone. 99.9% of the time, the tone won't do anything and you'll be SoL, but when that magic frequency comes up, BAM, you walk out scott free.

Don't get me wrong, I'm SUPER interested in this trick, and ever since reading Parasite Rex by Carl Zimmer have been enthralled by viruses/parasites as a means for controlling unbalanced populations of anything (crop pests, bacteria in people, the mold that fastidiously grows in the grout, etc), because frankly, nature does it better then we ever can.
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Re: Fight infections with virus

Postby The Reaper » Thu Jun 18, 2009 2:53 am UTC

Izawwlgood wrote:There are plenty of bacteria immune to plenty of viruses. And, plenty of bacteria evolve to be immune to a virus they were once susceptible to.

This idea is pretty old and I think can sort of be equated to fighting your way out of a house made of thick glass with a megaphone cranking a single, random tone. 99.9% of the time, the tone won't do anything and you'll be SoL, but when that magic frequency comes up, BAM, you walk out scott free.

Don't get me wrong, I'm SUPER interested in this trick, and ever since reading Parasite Rex by Carl Zimmer have been enthralled by viruses/parasites as a means for controlling unbalanced populations of anything (crop pests, bacteria in people, the mold that fastidiously grows in the grout, etc), because frankly, nature does it better then we ever can.

Take in account that every once in awhile your megaphone changes tones, and plays more tones simultaneously without degrading the sound frequencies of the other tones whenever it does successfully make more megaphones......

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Re: Fight infections with virus

Postby 3.14chan » Thu Jun 18, 2009 4:06 am UTC

Yeah, but virus evolve too creating new species to invade those "immune" bacterias
antibiotics can't evolve, they don't reproduce. But we can try to make new ones.
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Re: Fight infections with virus

Postby 3.14chan » Thu Jun 18, 2009 4:14 am UTC

Also I said:
"there is no bacteria immune to EVERY virus"

Of course all bacterias are immune to a bunch of virus but no bacteria is immune to every virus but there is bacteria immune to every antibiotic
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Re: Fight infections with virus

Postby BlackSails » Thu Jun 18, 2009 6:14 am UTC

3.14chan wrote: there is bacteria immune to every antibiotic


No, there are not.


Anyway, this isnt just throwing a whole bunch of viruses at someone and hoping one works. You have to culture the bacteria, and then your infectious disease specialists ID the strain and sequence it to look for particular genes and then hand you the vial with the proper virus. This only works if you have a virus prepared beforehand (or can order one from someone who does)

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Re: Fight infections with virus

Postby Duban » Thu Jun 18, 2009 6:30 pm UTC

Izawwlgood wrote:There are plenty of bacteria immune to plenty of viruses. And, plenty of bacteria evolve to be immune to a virus they were once susceptible to.

See that fails to really hold up to the virus's potential. Sure the Bacteria can evolve to be immune to the virus, but then the virus evolves to be able to affect the bacteria :-).
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Re: Fight infections with virus

Postby Vieto » Thu Jun 18, 2009 6:33 pm UTC

Duban wrote:
Izawwlgood wrote:There are plenty of bacteria immune to plenty of viruses. And, plenty of bacteria evolve to be immune to a virus they were once susceptible to.

See that fails to really hold up to the virus's potential. Sure the Bacteria can evolve to be immune to the virus, but then the virus evolves to be able to affect the bacteria :-).

Or us :mrgreen:
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Re: Fight infections with virus

Postby The Reaper » Thu Jun 18, 2009 6:45 pm UTC

Vieto wrote:
Duban wrote:
Izawwlgood wrote:There are plenty of bacteria immune to plenty of viruses. And, plenty of bacteria evolve to be immune to a virus they were once susceptible to.

See that fails to really hold up to the virus's potential. Sure the Bacteria can evolve to be immune to the virus, but then the virus evolves to be able to affect the bacteria :-).

Or us :mrgreen:

As I understand it, bacteriophages can't infect eukaryotic cells, or whatever the name was for non-bacteria, -shrug-

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Re: Fight infections with virus

Postby 3.14chan » Thu Jun 18, 2009 8:35 pm UTC

I think that people should see the video first. I know that it is long (50 min WTF) but today there is some multi resistant bacteria, and we are always behind bacteria in developing new antibiotics. There are bacterias resistant to our most advanced antibiotics out there.
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Re: Fight infections with virus

Postby Izawwlgood » Thu Jun 18, 2009 8:51 pm UTC

I mean, there's about as much danger of a bacteriophase infecting us as there is shooting victim dying from lightening strike.

MRSA is a good example of a very resistant bacteria, that this treatment would be perfect for (just keep a culture of staph killing viruses handy).
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Re: Fight infections with virus

Postby 3.14chan » Thu Jun 18, 2009 9:30 pm UTC

Izawwlgood wrote:I mean, there's about as much danger of a bacteriophase infecting us as there is shooting victim dying from lightening strike.

MRSA is a good example of a very resistant bacteria, that this treatment would be perfect for (just keep a culture of staph killing viruses handy).


The chances of a bacteriophage infect us is much smaller than to be hit by lightening 7 times in a year.
A mite virus would be nearer to infect us than a bacteriophage. (and we have mites everywhere)
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Re: Fight infections with virus

Postby Izawwlgood » Thu Jun 18, 2009 10:51 pm UTC

I meant getting shot, and actually dying because the lightening was attracted to the bullet, but I see my hyperbolic metaphor failed in clarity.
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Re: Fight infections with virus

Postby 3.14chan » Fri Jun 19, 2009 4:57 am UTC

Izawwlgood wrote:I meant getting shot, and actually dying because the lightening was attracted to the bullet, but I see my hyperbolic metaphor failed in clarity.

maybe because english is not my mother language? (I'm not from a english speaking country)

Anyway, phages are so especific that they only infect one species of bacteria.
The chances of one infect an animal or vegetal or fungus is the same as the chance of a rafflesia attack you and suck your blood instead of a Tetrastigma vine.
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Re: Fight infections with virus

Postby General_Norris » Fri Jun 19, 2009 9:07 am UTC

Do you know something bad about this?

Human stupidity. I can totally see screams of "BUT THEY ARE VIRUSES"

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Re: Fight infections with virus

Postby 3.14chan » Fri Jun 19, 2009 12:45 pm UTC

General_Norris wrote:Do you know something bad about this?

Human stupidity. I can totally see screams of "BUT THEY ARE VIRUSES"


Today we have probiotic yogurt, probiotic ice cream, probiotic this and probiotic that...

Maybe in future we will have virus in probiotic bubblegum to reduce acid-producing bacteria from our mouth.
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Re: Fight infections with virus

Postby General_Norris » Fri Jun 19, 2009 1:10 pm UTC

^I think you missed my point

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Re: Fight infections with virus

Postby 3.14chan » Fri Jun 19, 2009 1:56 pm UTC

No no. I just said that today people think that this is weird but in future they will not.

Think about eat food full of bacteria sounds bad but prebiotics are food full of bacteria and people see them as something good.

The same will be with virus. Today it is weird/scary but them someone give it a cool name and people will pay for it.

Today we pay more for a yogurt full of bacteria than for a normal one.but they don't say that they are full of bacteria, they say probiotic :roll:
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